CRLS1 antibody (Middle Region)

Catalog No. ABIN2783750

There is 1 publication for this product available. The Rabbit Polyclonal anti-CRLS1 antibody is suitable to detect CRLS1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for CRLS1 antibody (Middle Region) (ABIN2783750)

Target: CRLS1 (CLS) (Cardiolipin Synthase (CLS))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRLS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CRLS1 Antibody

Binding Specificity: Middle Region

Purpose: CRLS1 Antibody - middle region

Sequence: WTIPNMLSMT RIGLAPVLGY LIIEEDFNIA LGVFALAGLT DLLDGFIARN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CRLS1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CRLS1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49444-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-CRLS1 antibody (ABIN2783750)

Croston, Shepherd, Thapa, Nichols, Lewis, Dabkowski, Jagannathan, Baseler, Hollander: "Evaluation of the cardiolipin biosynthetic pathway and its interactions in the diabetic heart." in: Life sciences, Vol. 93, Issue 8, pp. 313-22, (2013) (PubMed).

Target Details for CRLS1

Target: CRLS1 (CLS) (Cardiolipin Synthase (CLS))

Alternative Name: CRLS1

Background:

Background Information: CRLS1 catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.

Gene Name: Cardiolipin synthase 1

Alternative Symbols: CLS, CLS1, GCD10, C20orf155, dJ967N21.6

Protein Name: Cardiolipin synthase

Molecular Weight: 33 kDa

Gene ID: 54675

NCBI Accession: NP_061968

UniProt: Q9UJA2