FAM20C antibody (Middle Region)

Catalog No. ABIN2783771

This Rabbit Polyclonal antibody specifically detects FAM20C in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow and Zebrafish (Danio rerio).

Quick Overview for FAM20C antibody (Middle Region) (ABIN2783771)

Target: FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM20C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FAM20C Antibody

Binding Specificity: Middle Region

Purpose: FAM20C Antibody - middle region

Sequence: CFYGECSYYC STEHALCGKP DQIEGSLAAF LPDLSLAKRK TWRNPWRRSY

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against FAM20C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FAM20C

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49489-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FAM20C

Target: FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))

Alternative Name: FAM20C

Background:

Background Information: FAM20C belongs to the FAM20 family. FAM20C is a calcium-binding protein which may play a role in dentin mineralization. Mutations in FAM20C are associated with lethal osteosclerotic bone dysplasia (Raine Syndrome), highlighting a crucial molecule in bone development.

Gene Name: Family with sequence similarity 20, member C

Alternative Symbols: RNS, DMP4, G-CK, DMP-4, GEF-CK

Protein Name: Extracellular serine/threonine protein kinase Fam20C

Molecular Weight: 66kDa

Gene ID: 56975

NCBI Accession: NP_064608

UniProt: Q8IXL6