PLXDC1 antibody (N-Term)

Catalog No. ABIN2783776

The Rabbit Polyclonal anti-PLXDC1 antibody (ABIN2783776) specifically detects PLXDC1 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig and Rabbit samples.

Quick Overview for PLXDC1 antibody (N-Term) (ABIN2783776)

Target: PLXDC1 (Plexin Domain Containing 1 (PLXDC1))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLXDC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PLXDC1 Antibody

Binding Specificity: N-Term

Purpose: PLXDC1 Antibody - N-terminal region

Sequence: MDTLPDNRTR VVEDNHSYYV SRLYGPSEPH SRELWVDVAE ANRSQVKIHT

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PLXDC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PLXDC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49500-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PLXDC1

Target: PLXDC1 (Plexin Domain Containing 1 (PLXDC1))

Alternative Name: PLXDC1

Background:

Background Information: PLXDC1 (TEM7) may play significant role in proliferation and maintenance of neovascular endothelial cells in fibrovascular membranes. TEM7 may be molecular target for new diagnostic and therapeutic strategies for proliferative diabetic retinopathy. The expression level of TEM7 closely parallels histology-based prognostication of osteogenic sarcoma metastasis and, therefore, it is a therapeutic target.

Gene Name: Plexin domain containing 1

Alternative Symbols: TEM3, TEM7

Protein Name: Plexin domain-containing protein 1

Molecular Weight: 54kDa

Gene ID: 57125

NCBI Accession: NP_065138

UniProt: Q8IUK5