Neuroligin 4 antibody (N-Term)

Catalog No. ABIN2783800

The Rabbit Polyclonal anti-Neuroligin 4 antibody is suitable to detect Neuroligin 4 in samples from Mouse, Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for Neuroligin 4 antibody (N-Term) (ABIN2783800)

Target: Neuroligin 4 (NLGN4)

Reactivity: Mouse, Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuroligin 4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Neuroligin 4 Antibody

Binding Specificity: N-Term

Purpose: NLGN4X Antibody - N-terminal region

Sequence: SILASYGNVI VITINYRLGI LGFLSTGDQA AKGNYGLLDQ IQALRWIEEN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against NLGN4X. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NLGN4X

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8106365

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Neuroligin 4

Target: Neuroligin 4 (NLGN4)

Alternative Name: NLGN4X

Background:

Background Information: NLGN4X is a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. It interacts with discs, large (Drosophila) homolog 4 (DLG4). NLGN4X might play a role in the autism and Asperger syndrome.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests. This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large (Drosophila) homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene.

Gene Name: Neuroligin 4, X-linked

Alternative Symbols: HLNX, HNL4X, NLGN4, ASPGX2, AUTSX2

Protein Name: Neuroligin-4, Y-linked

Molecular Weight: 92kDa

Gene ID: 57502

NCBI Accession: NP_065793

UniProt: Q8NFZ3

Pathways: Cell-Cell Junction Organization, Synaptic Membrane