ADAM30 antibody (N-Term)

Catalog No. ABIN2783839

The Rabbit Polyclonal anti-ADAM30 antibody is suitable to detect ADAM30 in samples from Human, Cow and Dog. It has been validated for WB.

Quick Overview for ADAM30 antibody (N-Term) (ABIN2783839)

Target: ADAM30 (ADAM Metallopeptidase Domain 30 (ADAM30))

Reactivity: Human, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM30 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ADAM30 Antibody

Binding Specificity: N-Term

Purpose: ADAM30 Antibody - N-terminal region

Sequence: RLLLPRHLRV FSFTEHGELL EDHPYIPKDC NYMGSVKESL DSKATISTCM

Predicted Reactivity: Cow: 85%, Dog: 77%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against ADAM30. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ADAM30

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49661-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ADAM30

Target: ADAM30 (ADAM Metallopeptidase Domain 30 (ADAM30))

Alternative Name: ADAM30

Background:

Background Information: ADAM30 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM30 gene is testis-specific and contains a polymorphic region, resulting in isoforms with varying numbers of C-terminal repeats.This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is testis-specific and contains a polymorphic region, resulting in isoforms with varying numbers of C-terminal repeats.

Gene Name: ADAM metallopeptidase domain 30

Alternative Symbols: svph4

Protein Name: Disintegrin and metalloproteinase domain-containing protein 30

Molecular Weight: 66kDa

Gene ID: 11085

NCBI Accession: NP_068566

UniProt: Q9UKF2