XYLT1 antibody (Middle Region)

Catalog No. ABIN2783856

The Rabbit Polyclonal anti-XYLT1 antibody (ABIN2783856) specifically detects XYLT1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for XYLT1 antibody (Middle Region) (ABIN2783856)

Target: XYLT1 (Xylosyltransferase I (XYLT1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XYLT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-XYLT1 Antibody

Binding Specificity: Middle Region

Purpose: XYLT1 Antibody - middle region

Sequence: RITNWNRKLG CKCQYKHIVD WCGCSPNDFK PQDFHRFQQT ARPTFFARKF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against XYLT1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human XYLT1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49700-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for XYLT1

Target: XYLT1 (Xylosyltransferase I (XYLT1))

Alternative Name: XYLT1

Background:

Background Information: This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.

Gene Name: Xylosyltransferase I

Alternative Symbols: XT1, XTI, XT-I, DBQD2, XYLTI, PXYLT1, xylT-I

Protein Name: Xylosyltransferase 1

Molecular Weight: 107kDa

Gene ID: 64131

NCBI Accession: NP_071449

UniProt: Q86Y38

Pathways: Glycosaminoglycan Metabolic Process