STRA6 antibody (N-Term)

Catalog No. ABIN2783865

Product Details anti-STRA6 Antibody

Target: STRA6 (Stimulated By Retinoic Acid 6 (STRA6))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STRA6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSSQPAGNQT SPGATEDYSY GSWYIDEPQG GEELQPEGEV PSCHTSIPPG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against STRA6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human STRA6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 667 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for STRA6

Target: STRA6 (Stimulated By Retinoic Acid 6 (STRA6))

Alternative Name: STRA6 (STRA6 Products)

Synonyms: MCOPCB8 antibody, MCOPS9 antibody, AI891933 antibody, RGD1307551 antibody, STRA6 antibody, im:7151282 antibody, wu:fc51h06 antibody, zgc:136689 antibody, mcops9 antibody, pp14296 antibody, stimulated by retinoic acid 6 antibody, stimulated by retinoic acid gene 6 antibody, stimulated by retinoic acid gene 6 homolog (mouse) antibody, STRA6 antibody, Stra6 antibody, stra6 antibody

Background: STRA6 may act as a high-affinity cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). STRA6 acts by removing retinol from RBP/RBP4 and transports it across the plasma membrane, where it can be metabolized. This mechanism does not depend on endocytosis. STRA6 binds to RBP/RBP4 with high affinity. STRA6 increases cellular retinol uptake from the retinol-RBP complex.
Alias Symbols: FLJ12541, MCOPS9, PP14296
Protein Interaction Partner: UBC, CLN3,
Protein Size: 667

Molecular Weight: 73 kDa

Gene ID: 64220

NCBI Accession: NM_022369, NP_071764

UniProt: Q9BX79

Pathways: Feeding Behaviour