RHBDF1 antibody (N-Term)

Catalog No. ABIN2783869

This Rabbit Polyclonal antibody specifically detects RHBDF1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for RHBDF1 antibody (N-Term) (ABIN2783869)

Target: RHBDF1 (Rhomboid 5 Homolog 1 (RHBDF1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHBDF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RHBDF1 Antibody

Binding Specificity: N-Term

Sequence: KDWEKAPEQA DLTGGALDRS ELERSHLMLP LERGWRKQKE GAAAPQPKVR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against RHBDF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RHBDF1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 855 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RHBDF1

Target: RHBDF1 (Rhomboid 5 Homolog 1 (RHBDF1))

Alternative Name: RHBDF1

Background: RHBDF1 is a seven-transmembrane protein with a long N-terminal cytoplasmic extension that comprises half of the polypeptide sequence, and is found in the endoplasmic reticulum and Golgi, but not on the cell surface. RHBDF1 has a pivotal role in sustaining growth signals in epithelial cancer cells and thus may serve as a therapeutic target for treating epithelial cancers.
Alias Symbols: C16orf8, Dist1, EGFR-RS, FLJ2235, FLJ22357, gene -89, gene -90, hDist1, gene-89, gene-90
Protein Interaction Partner: UBC, TGFA,
Protein Size: 855

Molecular Weight: 97 kDa

Gene ID: 64285

NCBI Accession: NM_022450, NP_071895

UniProt: Q96CC6

Pathways: EGFR Signaling Pathway, Growth Factor Binding