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ACSL4 antibody (N-Term)

ACSL4 Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783895
  • Target See all ACSL4 Antibodies
    ACSL4 (Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4))
    Binding Specificity
    • 10
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    N-Term
    Reactivity
    • 65
    • 17
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig
    Host
    • 62
    • 2
    • 1
    Rabbit
    Clonality
    • 61
    • 4
    Polyclonal
    Conjugate
    • 27
    • 7
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACSL4 antibody is un-conjugated
    Application
    • 60
    • 34
    • 21
    • 20
    • 10
    • 9
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    AKRIKAKPTS DKPGSPYRSV THFDSLAVID IPGADTLDKL FDHAVSKFGK
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against ACSL4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ACSL4
    Top Product
    Discover our top product ACSL4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 670 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ACSL4 (Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4))
    Alternative Name
    ACSL4 (ACSL4 Products)
    Synonyms
    acsl4 antibody, zgc:66186 antibody, ACSL4 antibody, ACS4 antibody, FACL4 antibody, LACS4 antibody, MRX63 antibody, MRX68 antibody, 9430020A05Rik antibody, AU018108 antibody, Facl4 antibody, Lacs4 antibody, Acs4 antibody, acs4 antibody, acsl3 antibody, facl4 antibody, lacs4 antibody, mrx63 antibody, mrx68 antibody, T32A16.20 antibody, T32A16_20 antibody, long-chain acyl-CoA synthetase 4 antibody, acyl-CoA synthetase long chain family member 4a antibody, acyl-CoA synthetase long-chain family member 4 antibody, acyl-CoA synthetase long chain family member 4 antibody, AcsL4 antibody, acyl-CoA synthetase long chain family member 3 antibody, Long-chain-fatty-acid--CoA ligase 4 antibody, acyl-CoA synthetase long-chain family member 4 S homeolog antibody, AMP-dependent synthetase and ligase family protein antibody, acsl4a antibody, ACSL4 antibody, acsL4 antibody, acsl3 antibody, acsl4 antibody, Acsl4 antibody, acsl4.S antibody, LACS4 antibody
    Background
    ACSL4 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.
    Alias Symbols: ACS4, FACL4, LACS4, MRX63, MRX68
    Protein Interaction Partner: UBC, TUBGCP3, TP53, SUMO2, HECW2, YWHAQ, PARK2, DSE, ACSL3, APP, UBD, ELAVL1, MINOS1, SPG20,
    Protein Size: 670
    Molecular Weight
    74 kDa
    Gene ID
    2182
    NCBI Accession
    NM_004458, NP_004449
    UniProt
    O60488
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