Plexin A2 antibody (N-Term)

Catalog No. ABIN2783972

There is 1 publication for this product available. The Rabbit Polyclonal anti-Plexin A2 antibody is suitable to detect Plexin A2 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for Plexin A2 antibody (N-Term) (ABIN2783972)

Target: Plexin A2 (Plxna2)

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plexin A2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Plexin A2 Antibody

Binding Specificity: N-Term

Purpose: PLXNA2 Antibody - N-terminal region

Sequence: SVASYVYNGY SVVFVGTKSG KLKKIRADGP PHGGVQYEMV SVLKDGSPIL

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PLXNA2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PLXNA2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49932-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-Plexin A2 antibody (ABIN2783972)

Budel, Shim, Feng, Zhao, Hisama, Strittmatter: "No association between schizophrenia and polymorphisms of the PlexinA2 gene in Chinese Han Trios." in: Schizophrenia research, Vol. 99, Issue 1-3, pp. 365-6, (2008) (PubMed).

Target Details for Plexin A2

Target: Plexin A2 (Plxna2)

Alternative Name: PLXNA2

Background:

Background Information: PLXNA2 is a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C.

Gene Name: Plexin A2

Alternative Symbols: OCT, PLXN2

Protein Name: Plexin-A2

Molecular Weight: 211kDa

Gene ID: 5362

NCBI Accession: NP_079455

UniProt: O75051