ADAM33 antibody (Middle Region)

Catalog No. ABIN2783975

The Rabbit Polyclonal anti-ADAM33 antibody is suitable to detect ADAM33 in samples from Human, Rat, Mouse, Dog, Horse, Pig, Cow, Guinea Pig and Rabbit. It has been validated for WB.

Quick Overview for ADAM33 antibody (Middle Region) (ABIN2783975)

Target: ADAM33 (ADAM Metallopeptidase Domain 33 (ADAM33))

Reactivity: Human, Rat, Mouse, Dog, Horse, Pig, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM33 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ADAM33 Antibody

Binding Specificity: Middle Region

Purpose: ADAM33 Antibody - middle region

Sequence: HDSAQLLTGR AFQGATVGLA PVEGMCRAES SGGVSTDHSE LPIGAAATMA

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ADAM33. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ADAM33

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8094040

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ADAM33

Target: ADAM33 (ADAM Metallopeptidase Domain 33 (ADAM33))

Alternative Name: ADAM33

Background:

Background Information: ADAM33 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM33 is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness.This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Gene Name: ADAM metallopeptidase domain 33

Alternative Symbols: C20orf153, DJ964F7.1

Protein Name: Disintegrin and metalloproteinase domain-containing protein 33

Molecular Weight: 62kDa

Gene ID: 80332

NCBI Accession: NP_079496

UniProt: Q9BZ11