Megakaryocyte and Platelet Inhibitory Receptor G6b (MPIG6B) (N-Term) antibody

Catalog No. ABIN2783980

This Rabbit Polyclonal antibody specifically detects Megakaryocyte and Platelet Inhibitory Receptor G6b in WB. It exhibits reactivity toward Human, Cow, Dog and Rat.

Quick Overview for Megakaryocyte and Platelet Inhibitory Receptor G6b (MPIG6B) (N-Term) antibody (ABIN2783980)

Target: Megakaryocyte and Platelet Inhibitory Receptor G6b (MPIG6B)

Reactivity: Human, Cow, Dog, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Purpose: MPIG6B Antibody - N-terminal region

Sequence: AVFLQLLPLL LSRAQGNPGA SLDGRPGDRV NLSCGGVSHP IRWVWAPSFP

Predicted Reactivity: Cow: 79%, Dog: 100%, Human: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against C6orf25. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C6orf25

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49948-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Megakaryocyte and Platelet Inhibitory Receptor G6b (MPIG6B)

Alternative Name: MPIG6B

Background:

Background Information: This gene is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. The protein encoded by this gene is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: megakaryocyte and platelet inhibitory receptor G6b

Alternative Symbols: G6b, NG31, G6b-B, THAMY, C6orf25

Protein Name: megakaryocyte and platelet inhibitory receptor G6b

Molecular Weight: 23kDa

Gene ID: 80739

NCBI Accession: NP_079536

UniProt: B0UXC6