PTDSS2 antibody (N-Term)

Catalog No. ABIN2783985

Cited in 1 publication. The Rabbit Polyclonal anti-PTDSS2 antibody (ABIN2783985) specifically detects PTDSS2 in WB. The antibody is reactive with Human, Dog, Guinea Pig, Mouse, Rat and Horse samples.

Quick Overview for PTDSS2 antibody (N-Term) (ABIN2783985)

Target: PTDSS2 (phosphatidylserine Synthase 2 (PTDSS2))

Reactivity: Human, Dog, Guinea Pig, Mouse, Rat, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTDSS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PTDSS2 Antibody

Binding Specificity: N-Term

Purpose: PTDSS2 Antibody - N-terminal region

Sequence: GQATGPGEGR RSTESEVYDD GTNTFFWRAH TLTVLFILTC TLGYVTLLEE

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PTDSS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PTDSS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49960-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-PTDSS2 antibody (ABIN2783985)

Iraji, St Germain, Grapentine, Perreira, Schenkel, Al-Douri, Hillyer, Cho, Ma, Bakovic: "Homeostatic response of phospholipid pathways to PCYT2 deficiency and impaired de Novo synthesis of phosphatidylethanolamine." in: Scientific reports, Vol. 15, Issue 1, pp. 38747, (2025) (PubMed).

Target Details for PTDSS2

Target: PTDSS2 (phosphatidylserine Synthase 2 (PTDSS2))

Alternative Name: PTDSS2

Background:

Background Information: Phosphatidylserine (PS) accounts for 5 to 10 % of cell membrane phospholipids. In addition to its role as a structural component, PS is involved in cell signaling, blood coagulation, and apoptosis. PS is synthesized by a calcium-dependent base-exchange reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS2, that exchange L-serine for the polar head group of phosphatidylcholine (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al., 2001 [PubMed 11084049]).

Gene Name: Phosphatidylserine synthase 2

Alternative Symbols: PSS2

Protein Name: Phosphatidylserine synthase 2

Molecular Weight: 56kDa

Gene ID: 81490

NCBI Accession: NP_110410

UniProt: Q9BVG9