H13 antibody (Middle Region)
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- Target See all H13 Antibodies
- H13 (Histocompatibility 13 (H13))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rabbit, Dog, Guinea Pig, Horse, Cow, Rat, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This H13 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- IKLVFPQDLL EKGLEADNFA MLGLGDIVIP GIFIALLLRF DISLKKNTHT
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 92%
- Characteristics
- This is a rabbit polyclonal antibody against H13. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product H13 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 378 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- H13 (Histocompatibility 13 (H13))
- Alternative Name
- H13 (H13 Products)
- Synonyms
- H13 antibody, IMP1 antibody, IMPAS antibody, IMPAS-1 antibody, MSTP086 antibody, PSENL3 antibody, PSL3 antibody, SPP antibody, SPPL1 antibody, dJ324O17.1 antibody, cb228 antibody, zgc:56660 antibody, zgc:86862 antibody, wu:fc11a06 antibody, h13 antibody, MGC68919 antibody, 1200006O09Rik antibody, 4930443L17Rik antibody, 5031424B04Rik antibody, AV020344 antibody, H-13 antibody, Hm13 antibody, Spp antibody, histocompatibility minor 13 antibody, histocompatibility (minor) 13 antibody, histocompatibility (minor) 13 L homeolog antibody, histocompatibility 13 antibody, HM13 antibody, hm13 antibody, hm13.L antibody, H13 antibody, Hm13 antibody
- Background
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H13 catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. It is required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides. Involved in the intramembrane cleavage of the integral membrane protein PSEN1 By similarity. It may play a role in graft rejection.
Alias Symbols: 1200006O09Rik, 4930443L17Rik, 5031424B04Rik, AV020344, H-13, Hm13, PSL3, Spp
Protein Size: 378 - Molecular Weight
- 42 kDa
- Gene ID
- 14950
- NCBI Accession
- NM_010376, NP_034506
- UniProt
- Q9D8V0
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