AMN antibody (N-Term)

Catalog No. ABIN2783997

The Rabbit Polyclonal anti-AMN antibody is suitable to detect AMN in samples from Human, Mouse, Dog, Rat, Cow, Guinea Pig, Horse and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for AMN antibody (N-Term) (ABIN2783997)

Target: AMN (Amnionless (AMN))

Reactivity: Human, Mouse, Dog, Rat, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AMN Antibody

Binding Specificity: N-Term

Purpose: AMN Antibody - N-terminal region

Sequence: NWSQNRTPCA GGAVEFPADK MVSVLVQEGH AVSDMLLPLD GELVLASGAG

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 86%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against AMN. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AMN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49982-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for AMN

Target: AMN (Amnionless (AMN))

Alternative Name: AMN

Background:

Background Information: The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila.

Gene Name: Amnionless homolog (mouse)

Alternative Symbols: IGS2, PRO1028, amnionless

Protein Name: Protein amnionless

Molecular Weight: 46kDa

Gene ID: 81693

NCBI Accession: NP_112205

UniProt: Q9BXJ7

Pathways: Lipid Metabolism