SGK196 antibody (N-Term)

Catalog No. ABIN2784029

This Rabbit Polyclonal antibody specifically detects SGK196 in WB. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Cow, Dog and Guinea Pig.

Quick Overview for SGK196 antibody (N-Term) (ABIN2784029)

Target: SGK196 (Protein Kinase Protein SgK196 (SGK196))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGK196 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SGK196 Antibody

Binding Specificity: N-Term

Purpose: POMK Antibody - N-terminal region

Sequence: CEELRTEVRQ LKRVGEGAVK RVFLSEWKEH KVALSQLTSL EMKDDFLHGL

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against FLJ23356. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FLJ23356

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50048-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SGK196

Target: SGK196 (Protein Kinase Protein SgK196 (SGK196))

Alternative Name: POMK

Background:

Background Information: This gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants.

Gene Name: protein-O-mannose kinase

Alternative Symbols: SGK196, MDDGA12, MDDGC12

Protein Name: protein O-mannose kinase

Molecular Weight: 40kDa

Gene ID: 84197

NCBI Accession: NP_115613

UniProt: Q9H5K3