JAM3 antibody (N-Term)

Catalog No. ABIN2784060

The Rabbit Polyclonal anti-JAM3 antibody (ABIN2784060) specifically detects JAM3 in WB. The antibody is reactive with Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse and Rabbit samples.

Quick Overview for JAM3 antibody (N-Term) (ABIN2784060)

Target: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAM3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-JAM3 Antibody

Binding Specificity: N-Term

Purpose: JAM3 Antibody - N-terminal region

Sequence: SSNRTPVVQE FESVELSCII TDSQTSDPRI EWKKIQDEQT TYVFFDNKIQ

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against JAM3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human JAM3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50121-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for JAM3

Target: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Alternative Name: JAM3

Background:

Background Information: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. JAM3, one member of the immunoglobulin superfamily, is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. JAM3 is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family.

Gene Name: Junctional adhesion molecule 3

Alternative Symbols: JAMC, JAM-2, JAM-3, JAM-C

Protein Name: Junctional adhesion molecule C

Molecular Weight: 28kDa

Gene ID: 83700

UniProt: Q9BX67