DIRC2 antibody (Middle Region)

Catalog No. ABIN2784064

This Rabbit Polyclonal antibody specifically detects DIRC2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Horse and Rabbit.

Quick Overview for DIRC2 antibody (Middle Region) (ABIN2784064)

Target: DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIRC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DIRC2 Antibody

Binding Specificity: Middle Region

Purpose: DIRC2 Antibody - middle region

Sequence: AAESSRAHIK DRIEAVLYAE FGVVCLIFSA TLAYFPPRPP LPPSVAAASQ

Predicted Reactivity: Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DIRC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DIRC2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50133-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DIRC2

Target: DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))

Alternative Name: DIRC2

Background:

Background Information: DIRC2 is a membrane-bound protein from the major facilitator superfamily of transporters. Disruption of DIRC2 by translocation has been associated with haplo-insufficiency and renal cell carcinomas. Alternatively spliced transcript variants have been described, but their biological validity has not yet been determined.This gene encodes a membrane-bound protein from the major facilitator superfamily of transporters. Disruption of this gene by translocation has been associated with haplo-insufficiency and renal cell carcinomas. Alternatively spliced transcript variants have been described, but their biological validity has not yet been determined. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence and transcripts to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

Gene Name: Disrupted in renal carcinoma 2

Alternative Symbols: RCC4, DIRC2

Protein Name: Disrupted in renal carcinoma protein 2

Molecular Weight: 52kDa

Gene ID: 84925

NCBI Accession: NP_116228

UniProt: Q96SL1