MMEL1 antibody (Middle Region)

Catalog No. ABIN2784086

The Rabbit Polyclonal anti-MMEL1 antibody is suitable to detect MMEL1 in samples from Human, Mouse, Rat, Guinea Pig, Cow, Dog and Horse. It has been validated for WB.

Quick Overview for MMEL1 antibody (Middle Region) (ABIN2784086)

Target: MMEL1 (Membrane Metallo-Endopeptidase-Like 1 (MMEL1))

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMEL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MMEL1 Antibody

Binding Specificity: Middle Region

Purpose: MMEL1 Antibody - middle region

Sequence: EVVVYGIPYL QNLENIIDTY SARTIQNYLV WRLVLDRIGS LSQRFKDTRV

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MMEL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MMEL1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8105141

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MMEL1

Target: MMEL1 (Membrane Metallo-Endopeptidase-Like 1 (MMEL1))

Alternative Name: MMEL1

Background:

Background Information: MMEL1 is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. MMEL1 is a type II transmembrane protein and is thought to be expressed as a secreted protein. The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart.

Gene Name: Membrane metallo-endopeptidase-like 1

Alternative Symbols: NL1, NL2, SEP, NEP2, MMEL2, NEPII

Protein Name: Membrane metallo-endopeptidase-like 1

Molecular Weight: 89 kDa

Gene ID: 79258

NCBI Accession: NP_258428

UniProt: Q495T6