Ethanolaminephosphotransferase 1 (SELENOI) (N-Term) antibody

Catalog No. ABIN1544106

The Rabbit Polyclonal anti-Ethanolaminephosphotransferase 1 antibody (ABIN1544106) specifically detects Ethanolaminephosphotransferase 1 in WB. The antibody is reactive with Cow, Dog, Horse, Human, Mouse, Pig, Rabbit and Rat samples.

Quick Overview for Ethanolaminephosphotransferase 1 (SELENOI) (N-Term) antibody (ABIN1544106)

Target: Ethanolaminephosphotransferase 1 (SELENOI)

Reactivity: Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Purpose: SELENOI Antibody - N-terminal region

Sequence: FMLLVFNFLL LTYFDPDFYA SAPGHKHVPD WVWIVVGILN FVAYTLDGVD

Predicted Reactivity: Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Seli. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Seli

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50191-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Ethanolaminephosphotransferase 1 (SELENOI)

Alternative Name: SELENOI

Background:

Background Information: The multi-pass transmembrane protein encoded by this gene belongs to the CDP-alcohol phosphatidyltransferase class-I family. It catalyzes the transfer of phosphoethanolamine from CDP-ethanolamine to diacylglycerol to produce phosphatidylethanolamine, which is involved in the formation and maintenance of vesicular membranes, regulation of lipid metabolism, and protein folding. This protein is a selenoprotein, containing the rare selenocysteine (Sec) amino acid at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.

Gene Name: selenoprotein I

Alternative Symbols: Ept1, Seli, RGD1560938

Protein Name: ethanolaminephosphotransferase 1

Molecular Weight: 43kDa

Gene ID: 362713

NCBI Accession: NP_001128226