ANKH antibody (N-Term)

Catalog No. ABIN2784109

This Rabbit Polyclonal antibody specifically detects ANKH in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse and Zebrafish (Danio rerio).

Quick Overview for ANKH antibody (N-Term) (ABIN2784109)

Target: ANKH (Ankylosis, Progressive Homolog (Mouse) (ANKH))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ANKH Antibody

Binding Specificity: N-Term

Sequence: SDLGYYIINK LHHVDESVGS KTRRAFLYLA AFPFMDAMAW THAGILLKHK

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ANKH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANKH

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 492 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ANKH

Target: ANKH (Ankylosis, Progressive Homolog (Mouse) (ANKH))

Alternative Name: ANKH

Background: ANKH regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ANK, CCAL2, CMDJ, CPPDD, FLJ27166, HANK, MANK
Protein Interaction Partner: UBC, RPSA, APOE,
Protein Size: 492

Molecular Weight: 54 kDa

Gene ID: 56172

NCBI Accession: NM_054027, NP_473368

UniProt: Q9HCJ1