COX3 antibody (C-Term)

Catalog No. ABIN2784116

Product Details anti-COX3 Antibody

Target: COX3 (COX-3) (Cytochrome C Oxidase Subunit 3 (COX-3))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FESPFTISDG IYGSTFFVAT GFHGLHVIIG STFLTICFIR QLMFHFTSKH

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against COX3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human COX3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 260 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for COX3

Target: COX3 (COX-3) (Cytochrome C Oxidase Subunit 3 (COX-3))

Alternative Name: COX3 (COX-3 Products)

Synonyms: COIII antibody, MTCO3 antibody, cytochrome c oxidase III antibody, cytochrome c oxidase subunit III antibody, cytochrome c oxidase subunit 3 antibody, cytochrome oxidasesubunit 3 antibody, COX3 antibody, cox3 antibody

Background: COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency). Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.
Alias Symbols: MTCO3, COIII
Protein Interaction Partner: RAC1, LIG4, Htt, SNCA,
Protein Size: 260

Molecular Weight: 29 kDa

Gene ID: 4514

NCBI Accession: NP_536849

UniProt: P00414