Tmc2 antibody (Middle Region)

Catalog No. ABIN2784124

This Rabbit Polyclonal antibody specifically detects Tmc2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for Tmc2 antibody (Middle Region) (ABIN2784124)

Target: Tmc2 (Transmembrane Channel-Like 2 (Tmc2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tmc2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Tmc2 Antibody

Binding Specificity: Middle Region

Purpose: TMC2 Antibody - middle region

Sequence: YCWCWDLEAG FPSYAEFDIS GNVLGLIFNQ GMIWMGSFYA PGLVGINVLR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TMC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TMC2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114379

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Tmc2

Target: Tmc2 (Transmembrane Channel-Like 2 (Tmc2))

Alternative Name: TMC2

Background:

Background Information: TMC2 is considered a member of transmembrane proteins family. The specific function of this gene is unknown, however, expression in the inner ear suggests that it may be crucial for normal auditory function. This gene is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown, however, expression in the inner ear suggests that it may be crucial for normal auditory function. Mutations in this gene may underlie hereditary disorders of balance and hearing. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-382 AF417580.2 1-382 383-569 DA769512.1 96-282 570-859 DA769512.1 286-575 860-2736 AF417580.2 860-2736 2737-3169 AL049712.12 30165-30597 c

Gene Name: Transmembrane channel-like 2

Alternative Symbols: C20orf145

Protein Name: Transmembrane channel-like protein 2

Molecular Weight: 102kDa

Gene ID: 117532

NCBI Accession: NP_542789

UniProt: Q8TDI7