PHF12 antibody (C-Term)

Catalog No. ABIN2784177

The Rabbit Polyclonal anti-PHF12 antibody is suitable to detect PHF12 in samples from Mouse, Human, Rat, Cow, Horse, Rabbit and Guinea Pig. It has been validated for WB.

Quick Overview for PHF12 antibody (C-Term) (ABIN2784177)

Target: PHF12 (PHD Finger Protein 12 (PHF12))

Reactivity: Mouse, Human, Rat, Cow, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PHF12 Antibody

Binding Specificity: C-Term

Purpose: PHF12 Antibody - C-terminal region

Sequence: NVLYSCDFSE KTPPTPPSSI VAKVQSVIRR RRHQKQDEEP SEEAAMMSSQ

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PHF12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PHF12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50416-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHF12

Target: PHF12 (PHD Finger Protein 12 (PHF12))

Alternative Name: PHF12

Background:

Background Information: PHF12 acts as a transcriptional repressor. It is involved in recruitment of functional SIN3A complexes to DNA. PHF12 represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). IT may also repress transcription in a SIN3A-independent manner through recruitment of functional AES complexes to DNA.

Gene Name: PHD finger protein 12

Alternative Symbols: PF1

Protein Name: PHD finger protein 12

Molecular Weight: 110kDa

Gene ID: 57649

NCBI Accession: NP_001028733

UniProt: Q96QT6