ING1 antibody (N-Term)

Catalog No. ABIN2784212

The Rabbit Polyclonal anti-ING1 antibody is suitable to detect ING1 in samples from Human. It has been validated for WB.

Quick Overview for ING1 antibody (N-Term) (ABIN2784212)

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ING1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ING1 Antibody

Binding Specificity: N-Term

Purpose: ING1 Antibody - N-terminal region

Sequence: SPAERLVAEA DEGGPSAITG MGLCFRCLLF SFSGRSGVEG GRVDLNVFGS

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against ING1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ING1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50511-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ING1

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Alternative Name: ING1

Background:

Background Information: ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.

Gene Name: Inhibitor of growth family, member 1

Alternative Symbols: p33, p47, p33ING1, p24ING1c, p33ING1b, p47ING1a

Protein Name: Inhibitor of growth protein 1

Molecular Weight: 47kDa

Gene ID: 3621

NCBI Accession: NP_005528

UniProt: Q9UK53

Pathways: Protein targeting to Nucleus, Autophagy