YAP1 antibody (C-Term)

Catalog No. ABIN2784221

This Rabbit Polyclonal antibody specifically detects YAP1 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Sheep, Cow, Horse, Pig and Rabbit.

Quick Overview for YAP1 antibody (C-Term) (ABIN2784221)

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Sheep, Cow, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-YAP1 Antibody

Binding Specificity: C-Term

Sequence: QLPTLEQDGG TQNPVSSPGM SQELRTMTTN SSDPFLNSGT YHSRDESTDS

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against YAP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human YAP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 504 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for YAP1

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Alternative Name: YAP1

Background: YAP1 is the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. YAP1 contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction.
Alias Symbols: YAP, YAP2, YAP65, YKI
Protein Interaction Partner: ABL1, TP73, RUNX1, AMOT, UBC, FBXW7, ARFIP1, RTF1, PAPOLA, PRMT3, TOM1, TSNAX, STAT1, MAP2K1, NF2, WBP2, RASSF8, YWHAQ, INADL, RAPGEF2, TJP2, SLC9A3R2, PDLIM7, LATS1, MPDZ, RAE1, ARID1A, YWHAZ, YWHAH, YWHAG, YWHAE, YWHAB, TP53BP2, TEAD3, TEAD1, SMARCD1, D
Protein Size: 504

Molecular Weight: 54 kDa

Gene ID: 10413

NCBI Accession: NM_001130145, NP_001123617

UniProt: P46937

Pathways: MAPK Signaling, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha