LIMD1 antibody (N-Term)

Catalog No. ABIN2784238

The Rabbit Polyclonal anti-LIMD1 antibody has been validated for WB and IHC. It is suitable to detect LIMD1 in samples from Mouse, Human, Cow, Dog, Guinea Pig, Rat, Rabbit and Zebrafish (Danio rerio).

Quick Overview for LIMD1 antibody (N-Term) (ABIN2784238)

Target: LIMD1 (LIM Domains Containing 1 (LIMD1))

Reactivity: Mouse, Human, Cow, Dog, Guinea Pig, Rat, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIMD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-LIMD1 Antibody

Binding Specificity: N-Term

Sequence: MDKYDDLGLE ASKFIEDLNM YEASKDGLFR VDKGAGNNPE FEETRRVFAT

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against LIMD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LIMD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 503 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LIMD1

Target: LIMD1 (LIM Domains Containing 1 (LIMD1))

Alternative Name: LIMD1

Background: LIMD1 may be involved in cell anchoring via focal adhesions and in the cell cycle, particularly during mitosis. LIMD1 functionally interacts with pRB and the loss of which promotes lung carcinogenesis. Some breast tumors also have altered expression of LIMD1 RNA. LIMD1 may represent a critical tumor suppressor gene.
Alias Symbols: -
Protein Interaction Partner: NEDD8, SUMO1, UBA6, UBR7, C9orf78, FKBP9, EHD1, GTF3C4, PYGB, PLCG1, LATS2, LATS1, gag-pol, HIPK3, APP, DSTN, IGBP1, SQSTM1, EGLN3, EGLN2, EGLN1, VHL, STAC, UBC, RARA, RPP14,
Protein Size: 503

Molecular Weight: 56 kDa

Gene ID: 8994

NCBI Accession: NM_014240

UniProt: Q9UGP4

Pathways: Ribonucleoprotein Complex Subunit Organization