CTBP2 antibody (C-Term)

Catalog No. ABIN2784279

The Rabbit Polyclonal anti-CTBP2 antibody has been validated for WB and IHC. It is suitable to detect CTBP2 in samples from Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse and Rabbit.

Quick Overview for CTBP2 antibody (C-Term) (ABIN2784279)

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTBP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CTBP2 Antibody

Binding Specificity: C-Term

Sequence: TGRIPESLRN CVNKEFFVTS APWSVIDQQA IHPELNGATY RYPPGIVGVA

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CTBP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CTBP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 985 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CTBP2

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Alternative Name: CTBP2

Background: This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3, however, it was noted that similar loci elsewhere in the genome are likely.This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3, however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10.
Alias Symbols: -
Protein Interaction Partner: NOL4, TGIF1, HOXB5, NOL4L, FUNDC1, FOXP2, RIMBP3, LCOR, ZNF750, DMRTB1, TSHZ3, BCAS3, BAZ2B, PLCB1, IKZF2, RAI2, ZBTB18, IKZF1, CTBP1, FLI1, SUMO2, SUMO3, SPRTN, SMAD6, UBC, SUMO1, NEDD8, TRNT1, DDX19B, SGTA, DYRK1B, NRIP1, ZNF512B, C15orf39, CTPS2, PPP1R
Protein Size: 985

Molecular Weight: 106 kDa

Gene ID: 1488

NCBI Accession: NM_022802, NP_073713

UniProt: P56545