Cyclin L2 antibody (N-Term)

Catalog No. ABIN2784289

This Rabbit Polyclonal antibody specifically detects Cyclin L2 in WB. It exhibits reactivity toward Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for Cyclin L2 antibody (N-Term) (ABIN2784289)

Target: Cyclin L2 (CCNL2)

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin L2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cyclin L2 Antibody

Binding Specificity: N-Term

Sequence: TGQVLFQRFF YTKSFVKHSM EHVSMACVHL ASKIEEAPRR IRDVINVFHR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CCNL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CCNL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 226 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cyclin L2

Target: Cyclin L2 (CCNL2)

Alternative Name: CCNL2

Background: CCNL2 belongs to the cyclin family, Cyclin L subfamily. CCNL2 is a transcriptional regulator which participates in regulating the pre-mRNA splicing process. CCNL2 also modulates the expression of critical apoptotic factor, leading to cell apoptosis.
Alias Symbols: ANIA-6B, DKFZp761A1210, DKFZp762O195, HCLA-ISO, HLA-ISO, PCEE, SB138, CCNM
Protein Interaction Partner: RUNDC3A, CSNK2A2, DYRK1A, SRSF7, POLR2A, CDK11B, SRSF2, CDK11A,
Protein Size: 226

Molecular Weight: 24 kDa

Gene ID: 81669

NCBI Accession: NM_001039577, NP_001034666

UniProt: Q96S94