Cyclin L2 antibody (AA 400-480)

Catalog No. ABIN7227664

The Rabbit Polyclonal anti-Cyclin L2 antibody is suitable to detect Cyclin L2 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for Cyclin L2 antibody (AA 400-480) (ABIN7227664)

Target: Cyclin L2 (CCNL2)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin L2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cyclin L2 Antibody

Binding Specificity: AA 400-480

Purpose: Rabbit Anti-CCNL2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CCNL2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CCNL2 protein at AA range: 400-480

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Cyclin L2

Target: Cyclin L2 (CCNL2)

Alternative Name: CCNL2

Background: Cyclin-L2, Paneth cell-enhanced expression proteinThe protein encoded by CCNL2 (Cyclin L2) belongs to the cyclin family. Through its interaction with several proteins, such as RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for CCNL2. Diseases associated with CCNL2 include Star Syndrome.

Molecular Weight: 57kD

Gene ID: 81669

UniProt: Q96S94