LIN9 antibody (N-Term)

Catalog No. ABIN2784349

This Rabbit Polyclonal antibody specifically detects LIN9 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for LIN9 antibody (N-Term) (ABIN2784349)

Target: LIN9 (Lin-9 Homolog (LIN9))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIN9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LIN9 Antibody

Binding Specificity: N-Term

Sequence: TRKLTRVEWG KIRRLMGKPR RCSSAFFEEE RSALKQKRQK IRLLQQRKVA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against LIN9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LIN9

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 490 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LIN9

Target: LIN9 (Lin-9 Homolog (LIN9))

Alternative Name: LIN9

Background: LIN9 belongs to the lin-9 family and acts as a tumor suppressor. It inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. LIN9 plays a role in the expression of genes required for the G1/S transition.
Alias Symbols: TGS, BARA, TGS1, Lin-9, BARPsv
Protein Interaction Partner: MYBL2, E2F4, RBL2, LIN54, LIN52, LIN37, RBL1, RBBP4, UBC, LIN9, TFDP2, TFDP1, MYBL1, RB1,
Protein Size: 490

Molecular Weight: 53 kDa

Gene ID: 286826

NCBI Accession: NM_001270409

UniProt: B1B046

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases