TCF23 antibody (Middle Region)

Catalog No. ABIN2784350

Product Details anti-TCF23 Antibody

Target: TCF23 (Transcription Factor 23 (TCF23))

Binding Specificity: Middle Region

Reactivity: Mouse, Cow, Dog, Horse, Human, Rabbit, Rat, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF23 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RQAFLALQAA LPAVPPDTKL SKLDVLVLAT SYIAHLTRTL GHELPGPAWP

Predicted Reactivity: Cow: 85%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Tcf23. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 209 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TCF23

Target: TCF23 (Transcription Factor 23 (TCF23))

Alternative Name: Tcf23 (TCF23 Products)

Synonyms: TCF23 antibody, 2010002O16Rik antibody, Out antibody, bHLHa24 antibody, OUT antibody, TCF-23 antibody, transcription factor 23 antibody, TCF23 antibody, Tcf23 antibody, tcf23 antibody

Background: Tcf23 inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Tcf23 inhibits the formation of TCF3 and MYOD1 homo- and heterodimers. Tcf23 lacks DNA binding activity. Tcf23 may be involved in the regulation or modulation of smooth muscle contraction of the uterus during pregnancy and particularly around the time of delivery. Tcf23 seems to play a role in the inhibition of myogenesis.
Alias Symbols: 2010002O16Rik, Out, bHLHa24
Protein Size: 209

Molecular Weight: 23 kDa

Gene ID: 69852

NCBI Accession: NM_053085, NP_444315

UniProt: Q9JLR5