TCF23 antibody (Middle Region)

Catalog No. ABIN2784350

The Rabbit Polyclonal anti-TCF23 antibody (ABIN2784350) specifically detects TCF23 in WB. The antibody is reactive with Mouse, Cow, Dog, Horse, Human, Rabbit, Rat, Guinea Pig and Pig samples.

Quick Overview for TCF23 antibody (Middle Region) (ABIN2784350)

Target: TCF23 (Transcription Factor 23 (TCF23))

Reactivity: Mouse, Cow, Dog, Horse, Human, Rabbit, Rat, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF23 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TCF23 Antibody

Binding Specificity: Middle Region

Purpose: Tcf23 Antibody - middle region

Sequence: RQAFLALQAA LPAVPPDTKL SKLDVLVLAT SYIAHLTRTL GHELPGPAWP

Predicted Reactivity: Cow: 85%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Tcf23. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50833-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TCF23

Target: TCF23 (Transcription Factor 23 (TCF23))

Alternative Name: Tcf23

Background:

Background Information: Tcf23 inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Tcf23 inhibits the formation of TCF3 and MYOD1 homo- and heterodimers. Tcf23 lacks DNA binding activity. Tcf23 may be involved in the regulation or modulation of smooth muscle contraction of the uterus during pregnancy and particularly around the time of delivery. Tcf23 seems to play a role in the inhibition of myogenesis.

Gene Name: Transcription factor 23

Alternative Symbols: Ou, Out, bHLHa, bHLHa24, 2010002O16Rik

Protein Name: Transcription factor 23

Molecular Weight: 23kDa

Gene ID: 69852

NCBI Accession: NP_444315

UniProt: Q9JLR5