ZFYVE1 antibody (N-Term)

Catalog No. ABIN2784353

The Rabbit Polyclonal anti-ZFYVE1 antibody (ABIN2784353) specifically detects ZFYVE1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit samples.

Quick Overview for ZFYVE1 antibody (N-Term) (ABIN2784353)

Target: ZFYVE1 (Zinc Finger, FYVE Domain Containing 1 (ZFYVE1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFYVE1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZFYVE1 Antibody

Binding Specificity: N-Term

Purpose: ZFYVE1 Antibody - N-terminal region

Sequence: GVPHEAKSRC RYSHQYDNRV YTCKACYERG EEVSVVPKTS ASTDSPWMGL

Predicted Reactivity: Cow: 92%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ZFYVE1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZFYVE1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50842-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZFYVE1

Target: ZFYVE1 (Zinc Finger, FYVE Domain Containing 1 (ZFYVE1))

Alternative Name: ZFYVE1

Background:

Background Information: ZFYVE1 contains two zinc-binding FYVE domains in tandem. This protein binds to phosphatidylinositol-3-phosphate (PtdIns3P) through its FYVE-type zinc finger. It displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternatively spliced transcript variants have been found for this gene, and they encode two isoforms with different sizes. The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes. This gene encodes a protein which contains two zinc-binding FYVE domains in tandem. This protein displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternatively spliced transcript variants have been found for this gene, and they encode two isoforms with different sizes.

Gene Name: Zinc finger, FYVE domain containing 1

Alternative Symbols: SR3, DFCP1, TAFF1, ZNFN2A1, PPP1R172

Protein Name: Zinc finger FYVE domain-containing protein 1

Molecular Weight: 40kDa

Gene ID: 53349

NCBI Accession: NP_848535

UniProt: Q9HBF4