ZFYVE1 antibody (N-Term)

Catalog No. ABIN2784353

Product Details anti-ZFYVE1 Antibody

Target: ZFYVE1 (Zinc Finger, FYVE Domain Containing 1 (ZFYVE1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFYVE1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GVPHEAKSRC RYSHQYDNRV YTCKACYERG EEVSVVPKTS ASTDSPWMGL

Predicted Reactivity: Cow: 92%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ZFYVE1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZFYVE1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 362 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZFYVE1

Target: ZFYVE1 (Zinc Finger, FYVE Domain Containing 1 (ZFYVE1))

Alternative Name: ZFYVE1 (ZFYVE1 Products)

Synonyms: DFCP1 antibody, SR3 antibody, TAFF1 antibody, ZNFN2A1 antibody, G630053K23 antibody, mKIAA1589 antibody, zinc finger FYVE-type containing 1 antibody, zinc finger FYVE-type containing 1 S homeolog antibody, zinc finger, FYVE domain containing 1 antibody, ZFYVE1 antibody, zfyve1.S antibody, Zfyve1 antibody

Background: ZFYVE1 contains two zinc-binding FYVE domains in tandem. This protein binds to phosphatidylinositol-3-phosphate (PtdIns3P) through its FYVE-type zinc finger. It displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternatively spliced transcript variants have been found for this gene, and they encode two isoforms with different sizes. The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes. This gene encodes a protein which contains two zinc-binding FYVE domains in tandem. This protein displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternatively spliced transcript variants have been found for this gene, and they encode two isoforms with different sizes.
Alias Symbols: DFCP1, KIAA1589, TAFF1, ZNFN2A1
Protein Interaction Partner: UBC, PPP1CA, APP, TRIM13, BCL2L1,
Protein Size: 362

Molecular Weight: 40 kDa

Gene ID: 53349

NCBI Accession: NM_178441, NP_848535