APOH antibody (N-Term)

Catalog No. ABIN2784436

This Rabbit Polyclonal antibody specifically detects APOH in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Pig, Rabbit and Horse.

Quick Overview for APOH antibody (N-Term) (ABIN2784436)

Target: APOH (Apolipoprotein H (Beta-2-Glycoprotein I) (APOH))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-APOH Antibody

Binding Specificity: N-Term

Purpose: APOH Antibody - N-terminal region

Sequence: LWPINTLKCT PRVCPFAGIL ENGAVRYTTF EYPNTISFSC NTGFYLNGAD

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 92%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against APOH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human APOH

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8094827

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for APOH

Target: APOH (Apolipoprotein H (Beta-2-Glycoprotein I) (APOH))

Alternative Name: APOH

Background:

Background Information: Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.

Gene Name: Apolipoprotein H (beta-2-glycoprotein I)

Alternative Symbols: BG, B2G1, B2GP1

Protein Name: Beta-2-glycoprotein 1

Molecular Weight: 36kDa

Gene ID: 350

NCBI Accession: NP_000033

UniProt: P02749