IL-33 antibody (N-Term)

Catalog No. ABIN2784443

This anti-IL-33 antibody is a Rabbit Polyclonal antibody detecting IL-33 in WB and IHC. Suitable for Human.

Quick Overview for IL-33 antibody (N-Term) (ABIN2784443)

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-33 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-IL-33 Antibody

Binding Specificity: N-Term

Sequence: AKEVCPMYFM KLRSGLMIKK EACYFRRETT KRPSLKTGRK HKRHLVLAAC

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against IL33. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IL33

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 270 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL-33

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Alternative Name: IL33

Background: Cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL33 induces T helper type 2-associated cytokines.
Alias Symbols: C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2, IL1F11
Protein Interaction Partner: USP21, UBC, CASP1, HIST2H2BE, HIST2H2AA3, CRMP1, IL1RL1,
Protein Size: 270

Molecular Weight: 31 kDa

Gene ID: 90865

NCBI Accession: NM_033439, NP_254274

UniProt: O95760

Pathways: Production of Molecular Mediator of Immune Response