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IL-33 antibody

IL33 Reactivity: Human WB, IHC (p), EIA, Func Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1449499
  • Target See all IL-33 (IL33) Antibodies
    IL-33 (IL33) (Interleukin 33 (IL33))
    Reactivity
    • 79
    • 46
    • 37
    • 9
    • 1
    Human
    Host
    • 102
    • 26
    • 4
    • 2
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 109
    • 29
    Polyclonal
    Conjugate
    • 68
    • 21
    • 13
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-33 antibody is un-conjugated
    Application
    • 82
    • 68
    • 35
    • 25
    • 18
    • 14
    • 14
    • 14
    • 11
    • 10
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Functional Studies (Func)
    Purification
    Affinity Chromatography employing immobilized hIL-33 matrix
    Immunogen
    Highly pure (>98%) E.coli derived recombinant Human Interleukin 33
    Top Product
    Discover our top product IL33 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Reconstitution
    Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
    Buffer
    PBS, pH 7.2 without preservatives
    Preservative
    Without preservative
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    IL-33 (IL33) (Interleukin 33 (IL33))
    Alternative Name
    Interleukin-33 (IL33) (IL33 Products)
    Synonyms
    IL33 antibody, C9orf26 antibody, DVS27 antibody, IL1F11 antibody, NF-HEV antibody, NFEHEV antibody, RP11-575C20.2 antibody, 9230117N10Rik antibody, Il-33 antibody, Il1f11 antibody, RGD1311155 antibody, interleukin 33 antibody, IL33 antibody, Il33 antibody
    Background
    Interleukin 33 (IL-33) is a 32 kDa proinflammatory cytokine and intracellular nuclear factor with transcriptional regulatory properties. IL-33 is structurally related to IL-1, which induces helper T-cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12 kDa and C-terminal fragment of 18 kDa by cleavage of caspase-1.Synonyms: C9orf26, IL-1F11, IL-33, IL1F11, Interleukin-1 family member 11, NF-HEV, NFHEV, Nuclear factor from high endothelial venules
    Gene ID
    90865
    NCBI Accession
    NP_001186569
    Pathways
    Production of Molecular Mediator of Immune Response
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