INTS12 antibody (C-Term)

Catalog No. ABIN2784468

The Rabbit Polyclonal anti-INTS12 antibody is suitable to detect INTS12 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for INTS12 antibody (C-Term) (ABIN2784468)

Target: INTS12 (Integrator Complex Subunit 12 (INTS12))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTS12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-INTS12 Antibody

Binding Specificity: C-Term

Purpose: Ints12 Antibody - C-terminal region

Sequence: SGNGNSATAG PTGSITSKTT SETSSSTSAS LKGPTSQESQ LNAMKRLQMV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against Ints12. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Rat Ints12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51222-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for INTS12

Target: INTS12 (Integrator Complex Subunit 12 (INTS12))

Alternative Name: Ints12

Background:

Background Information: Ints12 is a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.

Gene Name: integrator complex subunit 12

Alternative Symbols: Phf22

Protein Name: Integrator complex subunit 12

Molecular Weight: 50kDa

Gene ID: 295448

NCBI Accession: NP_001007641

UniProt: Q68FR3