PHF6 antibody (N-Term)

Catalog No. ABIN2784476

This anti-PHF6 antibody is a Rabbit Polyclonal antibody detecting PHF6 in WB. Suitable for Human, Mouse, Dog, Cow, Rat, Horse, Rabbit, Pig and Guinea Pig.

Quick Overview for PHF6 antibody (N-Term) (ABIN2784476)

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Reactivity: Human, Mouse, Dog, Cow, Rat, Horse, Rabbit, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PHF6 Antibody

Binding Specificity: N-Term

Sequence: VGQNHSEDGA PALLTTAPPP GLQPGAGGTP GGPGGGGAPP RYATLEHPFH

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PHF6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PHF6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 365 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHF6

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Alternative Name: PHF6

Background: PHF6 is a member of the plant homeodomain (PHD)-like finger (PHF) family. PHF6 is a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation that localizes to the nucleolus. Mutations affecting the coding region of its gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears.This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: BORJ, MGC14797, BFLS, CENP-31
Protein Interaction Partner: UBC, SUMO1, NEDD8, BMI1, HECW2, CAND1, CUL3, HDGF,
Protein Size: 365

Molecular Weight: 41 kDa

Gene ID: 84295

NCBI Accession: NM_032458, NP_115834

UniProt: Q8IWS0