PHF6 antibody (Isoform 1, N-Term)

Catalog No. ABIN6972521

Product Details anti-PHF6 Antibody

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Binding Specificity: Isoform 1, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF6 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: PHF6 is a member of the plant homeodomain finger (PHF) family, which has a potential rode in regulation of chromatin accessibility to lineage-specific transcription factors as part of the nucleosome remodeling and deacetylase (NuRD) epigenetic complex. PHF6 has been reported as a tumor suppressor in association with hematopoietic malignancies including T-cell acute lymphoblastic leukemia (T-ALL) and acute myeloid leukemia (AML). PHF6 may have tissue-specific expression, and is overexpressed in both breast and colorectal cancers. Germline mutations in PHF6 are the cause of the Börjeson-Forssman-Lehmann X-linked intellectual disability syndrome (BFLS). PHF6 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogen: This antibody was generated using a peptide from the N-terminal region of human PHF6 (PHD finger protein 6 isoform 1).

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for PHF6

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Alternative Name: PHF6 (PHF6 Products)

Synonyms: zgc:55403 antibody, wu:fa22g03 antibody, BFLS antibody, BORJ antibody, CENP-31 antibody, 2700007B13Rik antibody, 4931428F02Rik antibody, mKIAA1823 antibody, PHD finger protein 6 antibody, PHD finger protein 6 L homeolog antibody, phf6 antibody, phf6.L antibody, PHF6 antibody, Phf6 antibody

Molecular Weight: 45 kDa

NCBI Accession: NP_115834