CACYBP antibody (Middle Region)

Catalog No. ABIN2784483

This Rabbit Polyclonal antibody specifically detects CACYBP in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit and Guinea Pig.

Quick Overview for CACYBP antibody (Middle Region) (ABIN2784483)

Target: CACYBP (Calcyclin Binding Protein (CACYBP))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACYBP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CACYBP Antibody

Binding Specificity: Middle Region

Sequence: FTERSFDLLV KNLNGKSYSM IVNNLLKPIS VEGSSKKVKT DTVLILCRKK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CACYBP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CACYBP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 228 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CACYBP

Target: CACYBP (Calcyclin Binding Protein (CACYBP))

Alternative Name: CACYBP

Background: CACYBP is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin.The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: GIG5, MGC87971, PNAS-107, RP1-102G20.6, S100A6BP, SIP
Protein Interaction Partner: CTNNB1, HSP90AB1, FKBP5, FKBP4, RPAP3, FKBP8, SUGT1, CARM1, RNF41, IRS4, UBE2I, PRDX2, PRDX1, METTL1, AARS, IPO11, TPD52, PPP6R2, PINX1, NGFRAP1, VCAM1, UBC, ITGA4, FN1, CD8A, SIAH1, HSP90AA1, TP53BP1, HNRNPA0, CACYBP, SKP1, S100A6, MAPK1, Mapk13, STK3, O
Protein Size: 228

Molecular Weight: 26 kDa

Gene ID: 27101

NCBI Accession: NM_014412, NP_055227

UniProt: Q9HB71

Pathways: Response to Growth Hormone Stimulus