TNNT3 antibody (C-Term)

Catalog No. ABIN2784496

This Rabbit Polyclonal antibody specifically detects TNNT3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Horse, Dog and Goat.It has been mentioned in 1 publication

Quick Overview for TNNT3 antibody (C-Term) (ABIN2784496)

Target: TNNT3 (Fast Skeletal Troponin T (TNNT3))

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Horse, Dog, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNNT3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TNNT3 Antibody

Binding Specificity: C-Term

Purpose: TNNT3 Antibody - C-terminal region

Sequence: QLEIDKFEFG EKLKRQKYDI MNVRARVQML AKFSKKAGTP AKGKVGGRWK

Predicted Reactivity: Cow: 86%, Dog: 93%, Goat: 85%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TNNT3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TNNT3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51286-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-TNNT3 antibody (ABIN2784496)

Zhang, Birbrair, Wang, Taylor, Messi, Delbono: "Troponin T nuclear localization and its role in aging skeletal muscle." in: Age (Dordrecht, Netherlands), Vol. 35, Issue 2, pp. 353-70, (2013) (PubMed).

Target Details for TNNT3

Target: TNNT3 (Fast Skeletal Troponin T (TNNT3))

Alternative Name: TNNT3

Background:

Background Information: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Gene Name: Troponin T type 3 (skeletal, fast)

Alternative Symbols: TNTF, DA2B2, beta-TnTF

Protein Name: Troponin T, fast skeletal muscle

Molecular Weight: 30kDa

Gene ID: 7140

NCBI Accession: NP_001036245

UniProt: P45378