Paternally Expressed 10 (PEG10) (N-Term) antibody

Details for Product No. ABIN2784509, Supplier: Log in to see
Antigen
  • EDR
  • HB-1
  • MEF3L
  • Mar2
  • Mart2
  • RGAG3
  • AA407948
  • Edr
  • MyEF-3
  • paternally expressed 10
  • PEG10
  • Peg10
Epitope
N-Term
17
9
7
6
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit
110
25
17
6
6
3
2
1
1
1
Host
Rabbit
68
42
Clonality
Polyclonal
Conjugate
Un-conjugated
6
6
6
4
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
90
66
28
20
18
17
13
7
4
4
3
1
Options
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Immunogen The immunogen is a synthetic peptide directed towards the N-terminal region of Human PEG10
Blocking Peptide Blocking peptide for this product available: ABIN2184261
Sequence SMMTGRAARW ASAKLERSHY LMHNYPAFMM EMKHVFEDPQ RREVAKRKIR
Predicted Reactivity Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%
Characteristics This is a rabbit polyclonal antibody against PEG10. It was validated on Western Blot.
Purification Affinity Purified
Antigen
Alternative Name PEG10 (PEG10 Antibody Abstract)
Background This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene.
Alias Symbols: EDR, HB-1, MEF3L, Mar2, Mart2, RGAG3
Protein Interaction Partner: SIAH1, FAM127C, LDOC1, CALCOCO2, FAM127A, UBC, MAPT, HNRNPUL1, HNRNPH1, BAG1, TGFBR2, TGFBR1, BMPR1B, BMPR1A, ACVRL1, ACVR2B, ACVR2A, ACVR1B, ACVR1, RNF2, ZNF512B, RNF181, HMGCS1, TOLLIP, IRF4, SIAH2,
Protein Size: 708
Molecular Weight 80 kDa
Gene ID 23089
NCBI Accession NM_015068, NP_055883
UniProt Q86TG7
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeat freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Paternally Expressed 10 (PEG10) (N-Term) antibody (ABIN2784509) Host: Rabbit Target Name: PEG10 Sample Type: Lung Tumor lysates Antibody Diluti...
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