PEG10 antibody (N-Term)

Catalog No. ABIN2784509

The Rabbit Polyclonal anti-PEG10 antibody (ABIN2784509) specifically detects PEG10 in WB. The antibody is reactive with Human, Mouse, Rabbit, Cow, Horse, Dog and Guinea Pig samples.

Quick Overview for PEG10 antibody (N-Term) (ABIN2784509)

Target: PEG10 (Paternally Expressed 10 (PEG10))

Reactivity: Human, Mouse, Rabbit, Cow, Horse, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEG10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PEG10 Antibody

Binding Specificity: N-Term

Purpose: PEG10 Antibody - N-terminal region

Sequence: SMMTGRAARW ASAKLERSHY LMHNYPAFMM EMKHVFEDPQ RREVAKRKIR

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%

Characteristics: This is a rabbit polyclonal antibody against PEG10. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PEG10

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51313-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PEG10

Target: PEG10 (Paternally Expressed 10 (PEG10))

Alternative Name: PEG10

Background:

Background Information: This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene.

Gene Name: paternally expressed 10

Alternative Symbols: EDR, HB-1, Mar2, RTL2, MEF3L, Mart2, RGAG3, SIRH1

Protein Name: Retrotransposon-derived protein PEG10

Molecular Weight: 80kDa

Gene ID: 23089

NCBI Accession: NP_055883

UniProt: Q86TG7