TRIP6 antibody (N-Term)

Catalog No. ABIN2784547

Product Details anti-TRIP6 Antibody

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSGPTWLPPK QPEPARAPQG RAIPRGTPGP PPAHGAALQP HPRVNFCPLP

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TRIP6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIP6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 476 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TRIP6 antibody (ABIN2784547)

Johnson, Bai, Smith, Patel, Wang: "Single-molecule studies reveal dynamics of DNA unwinding by the ring-shaped T7 helicase." in: Cell, Vol. 129, Issue 7, pp. 1299-309, (2007) (PubMed).

Target Details for TRIP6

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Alternative Name: TRIP6 (TRIP6 Products)

Synonyms: TRIP6 antibody, OIP-1 antibody, OIP1 antibody, TRIP-6 antibody, TRIP6i2 antibody, ZRP-1 antibody, thyroid hormone receptor interactor 6 antibody, TRIP6 antibody, Trip6 antibody

Background: TRIP6 is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of TRIP6 to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration.This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC10556, MGC10558, MGC29959, MGC3837, MGC4423, OIP1, ZRP-1, OIP-1, TRIP-6, TRIP6i2
Protein Interaction Partner: FASLG, SLC25A6, ABI2, CREB5, STK16, NCK2, TPM3, TMSB4X, RFX3, RAD23A, PRKAA2, PRKAA1, PIN1, PDGFRB, NEDD9, LMO2, KIR2DL4, HOXB9, HLA-DPB1, GNAI2, CNTF, BYSL, ATP5O, RHOA, AQP1, KRTAP26-1, INCA1, CEP57L1, POM121L4P, RNF214, TTLL10, MSRB3, FAM154A, TEKT4, L
Protein Size: 476

Molecular Weight: 50 kDa

Gene ID: 7205

NCBI Accession: NM_003302, NP_003293

UniProt: Q15654

Pathways: Cell-Cell Junction Organization