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Synovial Sarcoma, X Breakpoint 2B (SSX2B) (N-Term) antibody

SSX2B Reactivity: Human, Dog, Mouse, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2784591
  • Target See all Synovial Sarcoma, X Breakpoint 2B (SSX2B) Antibodies
    Synovial Sarcoma, X Breakpoint 2B (SSX2B)
    Binding Specificity
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Dog, Mouse, Pig
    Host
    • 3
    Rabbit
    Clonality
    • 3
    Polyclonal
    Conjugate
    • 3
    Un-conjugated
    Application
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    IQKAFDDIAK YFSKEEWEKM KASEKIFYVY MKRKYEAMTK LGFKATLPPF
    Predicted Reactivity
    Dog: 75%, Human: 100%, Mouse: 82%, Pig: 85%
    Characteristics
    This is a rabbit polyclonal antibody against SSX2B. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human SSX2B
    Top Product
    Discover our top product SSX2B Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Synovial Sarcoma, X Breakpoint 2B (SSX2B)
    Alternative Name
    SSX2B (SSX2B Products)
    Background
    The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X,18)(p11.2,q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 6757, located about 45 kb upstream in the opposite orientation on chromosome X.
    Protein Size: 223
    Molecular Weight
    24 kDa
    Gene ID
    727837
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