PAR1 antibody (N-Term)

Catalog No. ABIN2784606

This anti-PAR1 antibody is a Rabbit Polyclonal antibody detecting PAR1 in WB. Suitable for Human and Guinea Pig.

Quick Overview for PAR1 antibody (N-Term) (ABIN2784606)

Target: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Reactivity: Human, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PAR1 Antibody

Binding Specificity: N-Term

Sequence: KYEPFWEDEE KNESGLTEYR LVSINKSSPL QKQLPAFISE DASGYLTSSW

Predicted Reactivity: Guinea Pig: 78%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against F2R. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human F2R

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 425 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PAR1

Target: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Alternative Name: F2R

Background: Coagulation factor II receptor(F2R) is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member.Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CF2R, HTR, PAR1, TR, PAR-1
Protein Interaction Partner: UBC, PROCR, CAV1, CHRD, ATP13A2, PDCD6IP, AP3D1, GNAQ, GNAI2, FLOT2, CHMP4A, GNAT1, GNA13, GNA12, SNX1, GPRASP1, ITGAV, PRTN3, F2, PLG, GNA15, ELANE, CTSG, CAPN1, MMP1,
Protein Size: 425

Molecular Weight: 47 kDa

Gene ID: 2149

NCBI Accession: NM_001992, NP_001983

UniProt: P25116

Pathways: Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus