AHCY antibody (N-Term)

Catalog No. ABIN2784617

This Rabbit Polyclonal antibody specifically detects AHCY in WB. It exhibits reactivity toward Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Horse, Rabbit and Pig.

Quick Overview for AHCY antibody (N-Term) (ABIN2784617)

Target: AHCY (Adenosylhomocysteinase (AHCY))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AHCY antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AHCY Antibody

Binding Specificity: N-Term

Sequence: SDKLPYKVAD IGLAAWGRKA LDIAENEMPG LMRMRERYSA SKPLKGARIA

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against AHCY. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AHCY

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 432 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AHCY

Target: AHCY (Adenosylhomocysteinase (AHCY))

Alternative Name: AHCY

Background: S-adenosylhomocysteine hydrolase catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family.S-adenosylhomocysteine hydrolase catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: SAHH
Protein Interaction Partner: ANKRD40, C1orf50, APPBP2, HUWE1, UBC, FUS, AHCY, SUMO2, SUMO3, SUMO1, NEDD8, ASB16, MSN, MC1R, HK1, HEXA, HDGF, FH, EEF1A2, DHX15, CAPZB, ATIC, ACAT2, H2AFV, NSFL1C, OGFOD1, PAPSS1, UBA3, TBCE, PYGL, HECW2, FBXO6, YWHAQ, gag-pol, PXN, DAB2, ATF2, TRAF3IP1
Protein Size: 432

Molecular Weight: 48 kDa

Gene ID: 191

NCBI Accession: NM_000687, NP_000678

UniProt: P23526