AHCY antibody (N-Term)

Catalog No. ABIN655151

The Rabbit Polyclonal anti-AHCY antibody is suitable to detect AHCY in samples from Mouse. It has been validated for WB, FACS and IHC (p).

Quick Overview for AHCY antibody (N-Term) (ABIN655151)

Target: AHCY (Adenosylhomocysteinase (AHCY))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AHCY antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB14650

Product Details anti-AHCY Antibody

Binding Specificity: AA 79-110, N-Term

Predicted Reactivity: B, Pr, Pig

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This AHCY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-110 amino acids from the N-terminal region of human AHCY.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for AHCY

Target: AHCY (Adenosylhomocysteinase (AHCY))

Alternative Name: AHCY

Background: S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 47716

Gene ID: 191

NCBI Accession: NP_000678, NP_001155238

UniProt: P23526