GCOM1 antibody (Middle Region)

Catalog No. ABIN2784651

The Rabbit Polyclonal anti-GCOM1 antibody is suitable to detect GCOM1 in samples from Human, Rat, Dog, Horse, Mouse, Rabbit, Cow, Guinea Pig, Saccharomyces cerevisiae and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for GCOM1 antibody (Middle Region) (ABIN2784651)

Target: GCOM1 (GRINL1A Complex Locus (GCOM1))

Reactivity: Human, Rat, Dog, Horse, Mouse, Rabbit, Cow, Guinea Pig, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCOM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GCOM1 Antibody

Binding Specificity: Middle Region

Purpose: Gcom1 Antibody - middle region

Sequence: VAQVENQLLK MKVESSQEAN AEVMREMTKK LYSQYEEKLQ EEQRKHSAEK

Predicted Reactivity: Cow: 85%, Dog: 77%, Guinea Pig: 93%, Horse: 85%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Yeast: 100%, Zebrafish: 75%

Characteristics: This is a rabbit polyclonal antibody against Gcom1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human Gcom1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51834-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GCOM1

Target: GCOM1 (GRINL1A Complex Locus (GCOM1))

Alternative Name: Gcom1

Background:

Background Information: This gene (Gcom1) is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts. The GRINL1A gene uses a downstream promoter for transcription and also has multiple alternatively spliced variants. This gene (Gcom1) is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts. The GRINL1A gene uses a downstream promoter for transcription and also has multiple alternatively spliced variants.

Gene Name: GRINL1A complex locus 1

Alternative Symbols: gcom, Gcom2, MYZAP, GRINL1A, MYZAP-POLR2M

Protein Name: Myocardial zonula adherens protein

Molecular Weight: 52kDa

Gene ID: 145781

NCBI Accession: NP_001018101

UniProt: P0CAP1