RDM1 antibody (Middle Region)

Catalog No. ABIN2784660

The Rabbit Polyclonal anti-RDM1 antibody has been validated for WB. It is suitable to detect RDM1 in samples from Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig and Pig.

Quick Overview for RDM1 antibody (Middle Region) (ABIN2784660)

Target: RDM1 (RAD52 Motif 1 (RDM1))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RDM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RDM1 Antibody

Binding Specificity: Middle Region

Sequence: NSSKCQELAN YYFGFNGCSK RIIKLQELSD LEERENEDSM VPLPKQSLKF

Predicted Reactivity: Cow: 83%, Dog: 93%, Guinea Pig: 91%, Human: 100%, Mouse: 83%, Pig: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RDM1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RDM1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 236 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RDM1

Target: RDM1 (RAD52 Motif 1 (RDM1))

Alternative Name: RDM1

Background: RDM1 is a protein involved in the cellular response to cisplatin, a drug commonly used in chemotherapy. It contains two motifs: a motif found in RAD52, a protein that functions in DNA double-strand breaks and homologous recombination, and an RNA recognition motif (RRM) that is not found in RAD52. The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization.This gene encodes a protein involved in the cellular response to cisplatin, a drug commonly used in chemotherapy. The protein encoded by this gene contains two motifs: a motif found in RAD52, a protein that functions in DNA double-strand breaks and homologous recombination, and an RNA recognition motif (RRM) that is not found in RAD52. The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization. Alternatively spliced transcript variants encoding different isoforms have been reported.
Alias Symbols: MGC33977, RAD52B
Protein Interaction Partner: MRFAP1L1, UBC,
Protein Size: 236

Molecular Weight: 26 kDa

Gene ID: 201299

NCBI Accession: NM_001034836, NP_001030008

UniProt: A8MY68