RDM1 antibody (AA 90-170)

Catalog No. ABIN7220260

The Rabbit Polyclonal anti-RDM1 antibody is suitable to detect RDM1 in samples from Human and Mouse. It has been validated for IHC, ELISA and IF.

Quick Overview for RDM1 antibody (AA 90-170) (ABIN7220260)

Target: RDM1 (RAD52 Motif 1 (RDM1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RDM1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-RDM1 Antibody

Binding Specificity: AA 90-170

Purpose: Rabbit Anti-RDM1 Polyclonal Antibody

Specificity: RDM1 Polyclonal Antibody detects endogenous levels of RDM1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human RDM1 at AA range: 90-170

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RDM1

Target: RDM1 (RAD52 Motif 1 (RDM1))

Alternative Name: RDM1

Background: RDM1, RAD52B, RAD52 motif-containing protein 1, RAD52 homolog BRDM1 encodes RAD52 motif containing 1 involved in the cellular response to cisplatin, a drug commonly used in chemotherapy. The RAD52 motif containing 1 encoded by RDM1 contains two motifs: a motif found in RAD52, a protein that functions in DNA double-strand breaks and homologous recombination, and an RNA recognition motif (RRM) that is not found in RAD52. The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization. Alternatively spliced transcript variants encoding different isoforms have been reported.

Gene ID: 201299

UniProt: Q8NG50